Definition of solvophobicity parameter

A solvent parameter defined by

Sp = 1 - M/M(hexadecane)

derived from the Gibbs energy of transfer (tGo) of a series of solutes from water to numerous aqueous-organic mixtures and to pure solvents:

tGo(to solvent) = MRT + D

where RT is a solute parameter, and M and D characterize the solvent. The M values are used to define a solvent solvophobic effect so that Sp values are scaled from unity (water) to zero (hexadecane). ABRAHAM, GRELLIER, and MCGILL (1988).