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Old April 9th, 2008, 23:29
ramanareddy_bhumireddy ramanareddy_bhumireddy is offline
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Default Regarding Amine Formation From Acid

I have Aromatic Acid group.i want to convert it to amine.Please tell me the feasible way.i got this but very very less yeild.
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Old April 22nd, 2010, 12:03
KathChem82 KathChem82 is offline
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First let an aromatic acid react with activated acid derivatives such as benzoyl chloride or by coupling reagents used in peptide synthesis such as N,N'-Dicyclohexylcarbodiimide and 4-Dimethylaminopyridine. the aromatic acid amide produced is then hydrolyzed to yield an amine and a carboxylic acid under strong acidic conditions.

hope this helps. ^_^
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