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Old December 26th, 2007, 13:27
sonar sonar is offline
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Default storage of glycogen in human body

in our body why only liver and muscles are able to store glycogen as storage energy source and why not other body orgens? means why nature has selected only these tow tissues only?
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Old December 30th, 2007, 11:22
Hix3r Hix3r is offline
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No glycongen is found in other organs as well in very low concentration, like in kidneys, white blood cells, glial cells and the brain. But yes liver and muscles are the main source.

Only the liver can store a glycogen storage that is accessible. Other cells that need glucose fast can't access the ones in muscle cells. And the liver is the first organ after glucose enters into your bloodstream from the entrails. This way, its purpose beside many things is to store the glucose, and if you would ever use it, make glucose and pump it to your bloodstream. Now it wouldn't be so smart to store glycogen in every cell or every organ would it? Why? Because when the glucose you ate, would reach those organs it would already disappear, because the cells on the way sucked it up! Also when you would need glucose because your running for example, the time every organ would get the signal to make glucose from glycogen, beside their usual function would would die.

Now muscles are different because they are the ones that need energy fast. For example when you are running a 100 m, in 10 seconds, you need massive energy to your muscles, but when you start running and the muscles use up your blood's glucose, the brain sends signal to the liver, and it hidrolizes glycogen and glucose enter into the bloodstream, and it makes it to your muscles, you are already done with running.

So it's best to store glycogen in muscles so they won't run out of energy until the glucose from the liver arrives.
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Old January 19th, 2010, 23:59
KathChem82 KathChem82 is offline
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Default glycogen

This is because the micromolecules that enter the body pass through the liver for chemical processes. In the liver, these nutrients are "checked" for their demand of and benefit for the body. If glucose molecules are not yet needed, then they will be stored in the liver as glycogen. Besides, the nutrients in the liver are directly passed onto the bloodstream. The liver has this capability of getting the nutrients into the bloodstream. It is true that in the muscles, glucose from glycogen cannot get into the bloodstream and so these glucose units are used locally. They are used to replenish the lost fuel due to muscle exertion. The muscles do not have the necessary enzymes to get these glucose units into the blood. The liver definitely has.
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