Thread: amide
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Old May 7th, 2005, 22:19
hemispheredancer hemispheredancer is offline
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Depending on what kind of other functional groups you have on the molecule there are a couple of ways you may be able to TLC this compound. First try I would use 95% CH2Cl2/5% MeOH with 1% NH3 added (you can add NH4OH). If this doesn't move it off the baseline then up the amount of MeOH/NH3 up to 10%. If this fails you can try to use a water/acetonitrile mix on silica TLC plates. If you can get your hands on C18 plates use those for the water/acetonitrile systems.