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Old August 24th, 2006, 01:52
logeshchem logeshchem is offline
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Default Another method

Hi, there's another method you may use to synthesize the desired compound.

Aniline + CF3COCl ---> C6H5NHCOCF3

The amide formed can be reduced with the use of LiAlH4 to obtain the amine, or the end product C6H5NHCH2CF3.

The second step is just hydride transfer from the hydride to the N-substituted amide.