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ramanareddy_bhumireddy April 10th, 2008 00:29

Regarding Amine Formation From Acid
 
I have Aromatic Acid group.i want to convert it to amine.Please tell me the feasible way.i got this but very very less yeild.

KathChem82 April 22nd, 2010 13:03

First let an aromatic acid react with activated acid derivatives such as benzoyl chloride or by coupling reagents used in peptide synthesis such as N,N'-Dicyclohexylcarbodiimide and 4-Dimethylaminopyridine. the aromatic acid amide produced is then hydrolyzed to yield an amine and a carboxylic acid under strong acidic conditions.

hope this helps. ^_^


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