- Wittig

(http://www.chemicool.com/chemtalk/index.php)

- Organic Chemistry (http://www.chemicool.com/chemtalk/forumdisplay.php?f=8)

- - Wittig (http://www.chemicool.com/chemtalk/showthread.php?t=566)

bobsacamano

June 20th, 2006 09:03

Wittig

I want to do a Wittig between MePPh3 and an aldehyde that is on the side chain of an amino acid. Any suggestions on what base I could use that would not result in racemization of my amino acid.

galy77

March 28th, 2007 09:51

Re: Wittig

Quote:

Originally Posted by bobsacamano

I want to do a Wittig between MePPh3 and an aldehyde that is on the side chain of an amino acid. Any suggestions on what base I could use that would not result in racemization of my amino acid.

I think you can use double stoichiometric potassium carbonate for this transformation and surely it will not racemize your aminoacid functionality.

All times are GMT -5. The time now is 16:30.