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bobsacamano

June 20th, 2006 08:03

Wittig

I want to do a Wittig between MePPh3 and an aldehyde that is on the side chain of an amino acid. Any suggestions on what base I could use that would not result in racemization of my amino acid.

galy77

March 28th, 2007 08:51

Re: Wittig

Quote:

Originally Posted by bobsacamano

I want to do a Wittig between MePPh3 and an aldehyde that is on the side chain of an amino acid. Any suggestions on what base I could use that would not result in racemization of my amino acid.

I think you can use double stoichiometric potassium carbonate for this transformation and surely it will not racemize your aminoacid functionality.

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